Dataset
First 10 rows of train
| _typestring | namestring | aliasesList | searchList | descriptionstring | related_drugsList | drug_interactionsList | food_interactionsList | pubmed_refsList | icd10string | prevalencestring | body_systemsList | source_diseasestring | clinician_personastring | patient_scenariostring | conversationList | common_mistakesList | differential_diagnosisList | related_diseasesList | executive_summarystring |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| disease_chatml | 22q11.2 deletion syndrome | ["DiGeorge syndrome","Velocardiofacial syndrome","VCFS","Shprintzen syndrome","Conotruncal anomaly face syndrome"] | ["22q11 deletion syndrome","digeorge syndrome","velocardiofacial syndrome","vcfs","chromosome 22q11","thymus aplasia conotruncal"] | 22q11.2 deletion syndrome is the most common chromosomal microdeletion disorder, caused by haploinsufficiency of genes within the 22q11.2 locus (including TBX1), resulting in a multisystem phenotype encompassing conotruncal cardiac defects (tetralogy of Fallot, interrupted aortic… | [{"din":"02237528","brand_name":"Neupogen","ingredient":"FILGRASTIM","atc_code":"L03AA02","role":"treatment"},{"din":"02242576","brand_name":"Gamimune N","ingredient":"IMMUNE GLOBULIN INTRAVENOUS","atc_code":"J06BA02","role":"treatment"},{"din":"00004723","brand_name":"Calcitriol… | [{"drug_a":"CALCITRIOL","drug_b":"THIAZIDE DIURETICS","severity":"moderate","description":"Thiazides increase calcium reabsorption; combined with calcitriol in hypoparathyroidism may cause hypercalcemia."},{"drug_a":"RISPERIDONE","drug_b":"QT-PROLONGING DRUGS","severity":"major",… | [] | [{"pmid":"24577245","title":"Psychiatric disorders from childhood to adulthood in 22q11.2 deletion syndrome: results from the International Consortium on Brain and Behavior in 22q11.2 Deletion Syndrome.","year":2014},{"pmid":"25569435","title":"Practical guidelines for managing a… | Q93.81 | ~1 in 2,000–4,000 live births; estimated 180,000 individuals in the US | ["cardiovascular","immunologic","endocrine","nervous","psychiatric"] | 22q11.2 deletion syndrome |
| Harpreet Kaur Sandhu is a 26-year-old Punjabi Indian-American woman who works as a bookkeeping assistant at her family's trucking company; she has 22q11.2 deletion syndrome diagnosed at age 19, repaired tetralogy of Fallot in infancy, hypoparathyroidism on calcitriol and calcium … |
| [{"role":"system","content":"You are Dr. Declan O'Rourke, an internist and clinical geneticist who directs an adult 22q11.2 deletion syndrome multidisciplinary clinic. Communicate with precision, cite evidence where it matters, correct numbers explicitly, and keep patient safety … |
| [{"mistake":"Raising calcitriol when hypocalcemia is really caused by missed calcium carbonate doses","explanation":"In 22q11.2-associated hypoparathyroidism a sudden fall in calcium on an unchanged regimen is most often nonadherence to bulky calcium tablets. Escalating calcitrio… |
| [{"condition":"Hypomagnesemia-induced functional hypoparathyroidism","differentiating_factors":"Low magnesium (often below 1.2 mg/dL) impairs PTH secretion and action; seen with PPIs, diuretics, alcohol, or diarrhea. Here magnesium is 1.9 mg/dL, excluding it."},{"condition":"Vita… |
| [{"disease":"Tetralogy of Fallot","relationship":"The most common conotruncal defect in 22q11.2 deletion syndrome; repaired patients need lifelong surveillance for pulmonary regurgitation, RBBB, and arrhythmia, which interacts with QT-prolonging drugs and hypocalcemia."},{"diseas… |
| ## 22q11.2 deletion syndrome: adult hypocalcemia with QT risk A 26-year-old woman with 22q11.2 deletion syndrome, repaired tetralogy of Fallot, hypoparathyroidism, humoral immunodeficiency, and new psychosis on **risperidone 1 mg nightly** presented with perioral paresthesia and… |
| disease_chatml | A fib | ["Atrial fibrillation","AF","AFib","Auricular fibrillation","Atrial arrhythmia"] | ["atrial fibrillation","a fib","afib","irregular heartbeat","atrial arrhythmia","heart rhythm disorder","stroke risk"] | Atrial fibrillation is a supraventricular tachyarrhythmia characterized by uncoordinated atrial activation with consequent deterioration of atrial mechanical function. It presents with palpitations, dyspnea, fatigue, and significantly elevated risk of cardioembolic stroke. Manage… | [{"din":"","brand_name":"Eliquis","ingredient":"APIXABAN","atc_code":"B01AF02","role":"treatment"},{"din":"","brand_name":"Xarelto","ingredient":"RIVAROXABAN","atc_code":"B01AF01","role":"treatment"},{"din":"","brand_name":"Coumadin","ingredient":"WARFARIN","atc_code":"B01AA03","… | [{"drug_a":"WARFARIN","drug_b":"AMIODARONE","severity":"major","description":"Amiodarone inhibits CYP2C9 and CYP3A4, markedly increasing warfarin levels and bleeding risk."},{"drug_a":"APIXABAN","drug_b":"RIFAMPIN","severity":"major","description":"Rifampin induces P-gp and CYP3A… | [{"food":"vitamin k","drug":"WARFARIN","severity":"major","mechanism":"anticoagulation reversal","description":"Vitamin K directly antagonizes warfarin anticoagulation — maintain consistent dietary intake"},{"food":"leafy greens","drug":"WARFARIN","severity":"major","mechanism":"… | [{"pmid":"21870978","title":"Apixaban versus warfarin in patients with atrial fibrillation.","year":2011},{"pmid":"21830957","title":"Rivaroxaban versus warfarin in nonvalvular atrial fibrillation.","year":2011},{"pmid":"32865375","title":"Early Rhythm-Control Therapy in Patients… | I48.91 | Affects approximately 33.5 million people worldwide; prevalence ~2-4% in adults over 40, rising to >10% in those over 80 | ["cardiovascular"] | A fib | Dr. Alejandro Ruiz Castañeda is a Mexican-American board-certified cardiologist and cardiac electrophysiologist practicing at a community heart and rhythm center in Sacramento, California, where he runs a rapid-access atrial fibrillation clinic. | Dmitri Aleksandrovich Sokolov is a 68-year-old Russian-American man, a part-time structural engineer who inspects bridges, with treated hypertension and daily ibuprofen use for knee osteoarthritis. He presents five days after onset of persistent palpitations and exertional dyspne… | [{"role":"system","content":"You are Dr. Alejandro Ruiz Castañeda, a board-certified cardiologist and cardiac electrophysiologist at a community heart and rhythm center in Sacramento, California. You are seeing a patient referred from urgent care with newly documented atrial fibr… | [{"mistake":"Accepting the patient's reported onset time and cardioverting without anticoagulation","explanation":"Patients frequently underestimate or misreport AF duration. When onset is uncertain or exceeds 48 hours, cardioversion requires at least 3 weeks of therapeutic antic… | [{"condition":"Atrial flutter","differentiating_factors":"Organized sawtooth flutter waves at about 300 per minute in II, III, aVF, often with regular 2:1 conduction producing a ventricular rate near 150 bpm, rather than an irregularly irregular rhythm without organized atrial ac… | [{"disease":"Ischemic stroke (cardioembolic)","relationship":"Left atrial appendage thrombus in AF embolizes to the cerebral circulation; AF raises stroke risk about fivefold, and anticoagulation reduces this by roughly two thirds."},{"disease":"Essential hypertension","relations… | ## Atrial fibrillation: new diagnosis, uncertain onset A 68-year-old man with hypertension presents with persistent palpitations, exertional dyspnea, and a ventricular rate of **112 bpm** despite low-dose metoprolol succinate. Labs are unremarkable apart from NT-proBNP **540 pg/… |
| disease_chatml | Abdominal aortic aneurysm | ["AAA","Aortic aneurysm abdominal","Infrarenal aortic aneurysm","Abdominal aortic dilation"] | ["abdominal aortic aneurysm","aaa","aortic dilation","abdominal aorta","vascular aneurysm","infrarenal aneurysm"] | Abdominal aortic aneurysm is a focal dilation of the infrarenal aorta exceeding 3 cm, caused by degradation of elastin and collagen in the arterial wall, often related to atherosclerosis. Most are asymptomatic until rupture, which presents with sudden severe abdominal or back pai… | [{"din":"","brand_name":"Lopressor","ingredient":"METOPROLOL TARTRATE","atc_code":"C07AB02","role":"treatment"},{"din":"","brand_name":"Lisinopril","ingredient":"LISINOPRIL","atc_code":"C09AA03","role":"treatment"},{"din":"","brand_name":"Lipitor","ingredient":"ATORVASTATIN","atc… | [{"drug_a":"CLOPIDOGREL","drug_b":"OMEPRAZOLE","severity":"moderate","description":"Omeprazole inhibits CYP2C19 and reduces conversion of clopidogrel to its active metabolite, decreasing antiplatelet effect."},{"drug_a":"ATORVASTATIN","drug_b":"CLARITHROMYCIN","severity":"moderat… | [{"food":"grapefruit","drug":"ATORVASTATIN","severity":"major","mechanism":"CYP3A4 inhibition","description":"Grapefruit inhibits intestinal CYP3A4, dramatically increasing statin plasma levels — risk of myopathy/rhabdomyolysis"}] | [{"pmid":"15978925","title":"Endovascular aneurysm repair versus open repair in patients with abdominal aortic aneurysm (EVAR trial 1): randomised controlled trial.","year":2005},{"pmid":"12000814","title":"Long-term outcomes of immediate repair compared with surveillance of smal… | I71.4 | Affects approximately 1-2% of the general population; prevalence 4-8% in men over 65, accounting for ~13,000 deaths per year in the US | ["cardiovascular"] | Abdominal aortic aneurysm | Dr. Javier Colón Figueroa is a Puerto Rican board-certified vascular surgeon, trained in San Juan and New York, who runs the aortic surveillance and endovascular repair program at a teaching hospital in Queens, New York. | Raymond (Wei-Ming) Chen is a 71-year-old Chinese-American man, a retired civil engineer for the New York City Department of Environmental Protection, with a 50 pack-year smoking history, hypertension, hyperlipidemia, and an NSTEMI treated with a drug-eluting LAD stent in November… | [{"role":"system","content":"You are Dr. Javier Colón Figueroa, a board-certified vascular surgeon at a teaching hospital in Queens, New York. You are seeing an established surveillance patient with a known infrarenal abdominal aortic aneurysm to review new CT angiography, preope… | [{"mistake":"Repairing small aneurysms (4.0 to 5.4 cm) early in asymptomatic men instead of surveillance.","explanation":"The UK Small Aneurysm Trial and the VA ADAM trial showed no survival benefit from immediate repair below 5.5 cm; operative risk exceeds the low rupture risk u… | [{"condition":"Tortuous or ectatic aorta without aneurysm","differentiating_factors":"A prominent pulsation in a thin patient may reflect a normal-caliber or ectatic aorta (below 3.0 cm, or less than 1.5 times normal); ultrasound or CT measurement of outer-to-outer diameter disti… | [{"disease":"Coronary artery disease","relationship":"Shares smoking, hypertension, and dyslipidemia as risk factors; it is the leading cause of death in AAA patients and drives the choice of repair modality and perioperative antiplatelet management."},{"disease":"Popliteal arter… | **Abdominal aortic aneurysm (I71.4)** in a 71-year-old Chinese-American man with a 50 pack-year smoking history and a drug-eluting LAD stent placed 10 months earlier. The infrarenal aneurysm grew from **4.3 to 5.7 cm** over two years and is now above the **5.5 cm** repair thresho… |
| disease_chatml | Abnormally excessive sweating | ["Hyperhidrosis","Primary hyperhidrosis","Focal hyperhidrosis","Diaphoresis","Excessive perspiration"] | ["hyperhidrosis","excessive sweating","diaphoresis","focal hyperhidrosis","palmar sweating","axillary hyperhidrosis"] | Hyperhidrosis is a condition characterized by sweating in excess of what is physiologically required for thermoregulation, affecting focal areas such as palms, soles, axillae, and craniofacial region. Primary focal hyperhidrosis has no identifiable cause, involves eccrine overact… | [{"din":"","brand_name":"Drysol","ingredient":"ALUMINUM CHLORIDE","atc_code":"D10AX","role":"treatment"},{"din":"","brand_name":"Botox","ingredient":"BOTULINUM TOXIN TYPE A","atc_code":"M03AX01","role":"treatment"},{"din":"","brand_name":"Robinul","ingredient":"GLYCOPYRROLATE","a… | [{"drug_a":"OXYBUTYNIN","drug_b":"AMANTADINE","severity":"moderate","description":"Combined anticholinergic effects increase risk of confusion, urinary retention, and heat stroke."},{"drug_a":"GLYCOPYRROLATE","drug_b":"METOCLOPRAMIDE","severity":"moderate","description":"Antichol… | [] | [{"pmid":"27744497","title":"Hyperhidrosis: an update on prevalence and severity in the United States.","year":2016},{"pmid":"30003988","title":"Topical glycopyrronium tosylate for the treatment of primary axillary hyperhidrosis: Results from the ATMOS-1 and ATMOS-2 phase 3 rando… | L74.510 | Affects approximately 4.8% of the US population (~15.3 million people); primary hyperhidrosis prevalence ~2.8% | ["dermatologic","nervous"] | Abnormally excessive sweating | Dr. Grace Mei-Ling Huang, MD, is a Chinese-American board-certified dermatologist who trained at UCSF and now directs a hyperhidrosis and procedural dermatology clinic at an academic medical center in Boston, where she performs iontophoresis setup, gravimetric testing, and botuli… | Nusrat Jahan Chowdhury is a 26-year-old Bangladeshi-Canadian woman who grew up in Toronto and relocated to Boston 18 months ago to work as a staff accountant at an audit firm; she has had drenching palmar and axillary sweating since age 13, was started on aluminum chloride by her… | [{"role":"system","content":"You are Dr. Grace Huang, a dermatologist specializing in hyperhidrosis. Take a focused history that distinguishes primary focal from secondary generalized hyperhidrosis, examine and quantify sweating, interpret laboratory screening, and build a stepwi… | [{"mistake":"Declaring topical aluminum chloride a failure without reviewing application technique and adherence","explanation":"Applying aluminum chloride to damp skin in the morning causes hydrochloric acid formation, severe stinging, and early discontinuation. Bedtime applicat… | [{"condition":"Hyperthyroidism","differentiating_factors":"Generalized rather than focal sweating, heat intolerance, weight loss, tremor, tachycardia, and lid lag; suppressed TSH with elevated free T4. Sweating persists during sleep."},{"condition":"Medication-induced hyperhidros… | [{"disease":"Secondary generalized hyperhidrosis","relationship":"Excess sweating driven by an underlying endocrine, neoplastic, infectious, neurologic, or pharmacologic cause; must be excluded when features are atypical for primary focal disease."},{"disease":"Compensatory hyper… | **Primary focal hyperhidrosis (ICD-10 L74.510)** in a 26-year-old accountant with adolescent-onset, bilateral palmar, plantar, and axillary sweating, positive family history, and cessation during sleep, meeting all six supportive diagnostic criteria. Examination showed visible pa… |
| disease_chatml | Abscess, Bartholin's | ["Bartholin gland abscess","Bartholin duct abscess","Bartholinitis","Bartholin cyst abscess"] | ["bartholin abscess","bartholin gland","vulvar abscess","bartholin cyst","bartholinitis","gland of bartholin"] | Bartholin's abscess is an acute infection of the Bartholin gland resulting from obstruction of the duct and secondary bacterial infection, presenting as a painful, fluctuant, unilateral labial mass at the 4 or 8 o'clock position. Common causative organisms include polymicrobial f… | [{"din":"","brand_name":"Augmentin","ingredient":"AMOXICILLIN CLAVULANATE","atc_code":"J01CR02","role":"treatment"},{"din":"","brand_name":"Flagyl","ingredient":"METRONIDAZOLE","atc_code":"J01XD01","role":"treatment"},{"din":"","brand_name":"Doxycycline","ingredient":"DOXYCYCLINE… | [{"drug_a":"METRONIDAZOLE","drug_b":"WARFARIN","severity":"major","description":"Metronidazole inhibits CYP2C9, significantly potentiating warfarin's anticoagulant effect and bleeding risk."},{"drug_a":"DOXYCYCLINE","drug_b":"ANTACIDS","severity":"moderate","description":"Divalen… | [{"food":"dairy","drug":"DOXYCYCLINE","severity":"moderate","mechanism":"chelation","description":"Calcium chelates tetracyclines/fluoroquinolones, reducing oral absorption by 50-80%"},{"food":"milk","drug":"DOXYCYCLINE","severity":"moderate","mechanism":"chelation","description"… | [{"pmid":"27640367","title":"Word catheter and marsupialisation in women with a cyst or abscess of the Bartholin gland (WoMan-trial): a randomised clinical trial.","year":2017},{"pmid":"31876985","title":"Evaluation of treatments for Bartholin's cyst or abscess: a systematic revi… | N75.1 | Affects approximately 2% of women during their lifetime; most common in women aged 20-29 years | ["reproductive"] | Abscess, Bartholin's | Dr. Natalia Volkova is a Russian-American board-certified obstetrician-gynecologist in a hospital-affiliated outpatient gynecology clinic, where she performs same-day office procedures including Word catheter placement and marsupialization for Bartholin gland disease. | Ayesha Qureshi is a 27-year-old Pakistani-American woman who works as a financial auditor. She presents with three days of a rapidly enlarging, painful left-sided vulvar swelling with fever, having secretly self-treated with two days of her sister's leftover amoxicillin before th… | [{"role":"system","content":"You are Dr. Natalia Volkova, a board-certified obstetrician-gynecologist working in a hospital-affiliated outpatient gynecology clinic with same-day procedure slots. You provide evidence-based, professionally worded care for vulvar and pelvic conditio… | [{"mistake":"Treating a fluctuant Bartholin abscess with antibiotics alone","explanation":"Antibiotics do not sterilize an established abscess cavity; drainage is the definitive treatment. Antibiotics are adjuncts when there is surrounding cellulitis, systemic signs, or risk fact… | [{"condition":"Bartholin duct cyst (non-infected)","differentiating_factors":"Painless or mildly uncomfortable, non-erythematous, non-tender fluctuant mass at 4 or 8 o'clock without fever or leukocytosis; may be observed if asymptomatic."},{"condition":"Vulvar cellulitis or folli… | [{"disease":"Bartholin duct cyst","relationship":"Duct obstruction produces the cyst, which can become secondarily infected and progress to an abscess."},{"disease":"Gonococcal and chlamydial infection","relationship":"Neisseria gonorrhoeae and Chlamydia trachomatis are occasiona… | **Bartholin gland abscess (N75.1)** in a 27-year-old woman: 3 days of a painful, fluctuant **4.0 x 3.5 cm** left 4 o'clock vestibular mass with 2 cm cellulitis, **T 38.2 C**, **HR 102 bpm**, **WBC 13.4 x10^9/L**, **CRP 46 mg/L**, normal glucose and HbA1c, negative hCG. Managed wi… |
| disease_chatml | Acanthosis nigricans | ["Hyperkeratosis nigricans","Acanthosis palmaris","Malignant acanthosis nigricans","AN"] | ["acanthosis nigricans","insulin resistance skin","hyperpigmentation skin folds","velvety skin","diabetes skin sign","dark neck skin"] | Acanthosis nigricans is a dermatological condition characterized by velvety, hyperpigmented, hyperkeratotic plaques in skin folds including the nape of the neck, axillae, and groin, most commonly associated with insulin resistance, obesity, and type 2 diabetes mellitus. The patho… | [{"din":"","brand_name":"Glucophage","ingredient":"METFORMIN","atc_code":"A10BA02","role":"treatment"},{"din":"","brand_name":"Retin-A","ingredient":"TRETINOIN","atc_code":"D10AD01","role":"treatment"},{"din":"","brand_name":"Lac-Hydrin","ingredient":"AMMONIUM LACTATE","atc_code"… | [{"drug_a":"METFORMIN","drug_b":"CONTRAST MEDIA","severity":"major","description":"Iodinated contrast may precipitate acute kidney injury, reducing metformin clearance and causing lactic acidosis."},{"drug_a":"TRETINOIN","drug_b":"TETRACYCLINES","severity":"major","description":"… | [{"food":"alcohol","drug":"METFORMIN","severity":"major","mechanism":"lactic acidosis","description":"Alcohol impairs hepatic gluconeogenesis — hypoglycemia and lactic acidosis risk"},{"food":"ethanol","drug":"METFORMIN","severity":"major","mechanism":"lactic acidosis","descripti… | [{"pmid":"36149039","title":"Insulin resistance in various grades of acanthosis nigricans.","year":2022},{"pmid":"33057385","title":"Acanthosis nigricans as a composite marker of cardiometabolic risk and its complex association with obesity and insulin resistance in Mexican Ameri… | L83 | Affects approximately 7.1% of the general US population; prevalence exceeds 74% in severely obese individuals with insulin resistance | ["dermatologic","endocrine"] | Acanthosis nigricans | Dr. Tarek Abdelmalek, MD, is an Egyptian-American internist with endocrinology fellowship training who runs a combined metabolic-dermatology clinic at a federally qualified community health center in San Antonio, Texas, serving a largely bilingual patient population. | Guadalupe Ramirez Ortega, a 34-year-old Mexican-American woman who works as kitchen manager of an elementary school cafeteria, presents with five years of progressive velvety darkening of the neck, axillae, and groin after 25 kg of postpartum weight gain and a history of gestatio… | [{"role":"system","content":"You are Dr. Tarek Abdelmalek, an internal medicine physician with endocrinology fellowship training who runs a combined metabolic-dermatology clinic at a community health center in San Antonio, Texas. Conduct a clinically rigorous, professional consul… | [{"mistake":"Treating acanthosis nigricans as a hygiene problem or infection","explanation":"Patients and some clinicians attribute the plaques to dirt or bacterial or fungal infection, leading to aggressive scrubbing, antibiotics, or antifungals. These do nothing for the hyperke… | [{"condition":"Confluent and reticulated papillomatosis (Gougerot-Carteaud)","differentiating_factors":"Scaly brown papules coalescing centrally with a reticulated periphery on the upper trunk and neck in young adults; typically responds to minocycline or doxycycline, whereas aca… | [{"disease":"Type 2 diabetes mellitus","relationship":"Acanthosis nigricans reflects hyperinsulinemia and predicts progression from prediabetes; most affected adults have or will develop impaired glucose regulation."},{"disease":"Polycystic ovary syndrome and HAIR-AN syndrome","r… | ## Acanthosis nigricans with insulin resistance A 34-year-old Mexican-American woman with prior gestational diabetes, BMI **38.3 kg/m2**, and five years of progressive velvety hyperpigmented plaques of the neck (Burke neck score 3), axillae, and groin. Workup showed prediabetes … |
| disease_chatml | Achalasia | ["Esophageal achalasia","Achalasia cardia","Cardio-esophageal achalasia","Primary achalasia","Mega-e | ["achalasia","esophageal motility disorder","dysphagia solids liquids","lower esophageal sphincter", | "Achalasia is a primary esophageal motor disorder characterized by failure of lower esophageal sphin | [{"din":"","brand_name":"Nitrostat","ingredient":"NITROGLYCERIN","atc_code":"C01DA02","role":"treatm | [{"drug_a":"NIFEDIPINE","drug_b":"RIFAMPIN","severity":"major","description":"Rifampin induces CYP3A | [{"food":"grapefruit","drug":"NIFEDIPINE","severity":"moderate","mechanism":"CYP3A4 inhibition","des | [{"pmid":"21561346","title":"Pneumatic dilation versus laparoscopic Heller's myotomy for idiopathic | K22.0 | "Incidence of approximately 1.6 per 100,000 per year; prevalence ~10 per 100,000; affects all ages w | ["digestive"] | Achalasia | "Dr. Tomasz Kowalczyk, MD, is a Polish-American gastroenterologist with fellowship training in esoph | "Rolando Echevarria is a 44-year-old Cuban-American man working as an HVAC technician, referred for | [{"role":"system","content":"You are Dr. Tomasz Kowalczyk, a gastroenterologist specializing in esop | [{"mistake":"Attributing dysphagia and regurgitation to GERD and escalating proton pump inhibitors", | [{"condition":"Pseudoachalasia (malignancy at the gastroesophageal junction)","differentiating_facto | [{"disease":"Esophageal squamous cell carcinoma","relationship":"Long-standing achalasia with food s | "**Achalasia (K22.0)** in a 44-year-old man with 2 years of dysphagia to solids and liquids, bland r |
| disease_chatml | Achilles tendinitis | ["Achilles tendinopathy","Achilles tendon inflammation","Midportion achilles tendinitis","Insertiona | ["achilles tendinitis","achilles tendinopathy","posterior heel pain","tendon inflammation","overuse | "Achilles tendinitis (tendinopathy) is a degenerative condition of the Achilles tendon characterized | [{"din":"","brand_name":"Advil","ingredient":"IBUPROFEN","atc_code":"M01AE01","role":"treatment"},{" | [{"drug_a":"IBUPROFEN","drug_b":"WARFARIN","severity":"major","description":"NSAIDs inhibit platelet | [{"food":"alcohol","drug":"ACETAMINOPHEN","severity":"major","mechanism":"hepatotoxicity","descripti | [{"pmid":"9617396","title":"Heavy-load eccentric calf muscle training for the treatment of chronic A | M76.60 | "Affects approximately 2.35 per 1,000 adults annually; lifetime risk in runners approximately 52%; a | ["musculoskeletal"] | Achilles tendinitis | "Dr. Linh Tran, MD, is a Vietnamese-American board-certified sports medicine physician who practices | "Francesca Russo is a 44-year-old Italian-American woman who works as a high school chemistry teache | [{"role":"system","content":"You are Dr. Linh Tran, a board-certified sports medicine physician. Con | [{"mistake":"Calling it an inflammatory tendinitis and treating it with rest plus NSAIDs alone","exp | [{"condition":"Achilles tendon rupture (partial or complete)","differentiating_factors":"Sudden pop | [{"disease":"Achilles tendon rupture","relationship":"Degenerative tendinopathy weakens the tendon a | "**Achilles tendinopathy (ICD-10 M76.60)** in a 44-year-old recreational runner after a rapid traini |
| disease_chatml | Achilles tendon rupture | ["Achilles tendon tear","Complete Achilles rupture","Tendo calcaneus rupture","Achilles tendon avuls | ["achilles tendon rupture","tendon tear","thompson test","heel cord rupture","sports injury tendon", | "Achilles tendon rupture is a complete or partial tear of the Achilles tendon, most commonly occurri | [{"din":"","brand_name":"Percocet","ingredient":"OXYCODONE ACETAMINOPHEN","atc_code":"N02AA05","role | [{"drug_a":"ENOXAPARIN","drug_b":"ASPIRIN","severity":"moderate","description":"Combination anticoag | [{"food":"alcohol","drug":"OXYCODONE ACETAMINOPHEN","severity":"contraindicated","mechanism":"additi | [{"pmid":"21037028","title":"Operative versus nonoperative treatment of acute Achilles tendon ruptur | S86.001A | "Incidence approximately 21-37 per 100,000 person-years; 3-4x more common in men than women; peak in | ["musculoskeletal"] | Achilles tendon rupture | "Dr. Thomas Whitaker, MD, FRCSC, is an American-born orthopaedic foot and ankle surgeon from Connect | "Mei Lin Huang is a 44-year-old Chinese-Canadian woman, a chartered professional accountant from Bur | [{"role":"system","content":"You are Dr. Thomas Whitaker, an orthopaedic foot and ankle surgeon at a | [{"mistake":"Missing the diagnosis because the patient can still walk and weakly plantarflex","expla | [{"condition":"Medial gastrocnemius strain (tennis leg)","differentiating_factors":"Pain and tendern | [{"disease":"Achilles tendinopathy","relationship":"Degenerative tendinosis is present in most ruptu | "## Acute Achilles tendon rupture: non-operative functional management\n\n**Patient:** 44-year-old w |
| disease_chatml | Acid reflux | ["Gastroesophageal reflux disease","GERD","Gastro-oesophageal reflux","Heartburn disease","Acid regu | ["acid reflux","gerd","heartburn","gastroesophageal reflux","regurgitation","lower esophageal sphinc | "Gastroesophageal reflux disease (GERD) is a chronic condition in which stomach acid and contents re | [{"din":"","brand_name":"Nexium","ingredient":"ESOMEPRAZOLE","atc_code":"A02BC05","role":"treatment" | [{"drug_a":"OMEPRAZOLE","drug_b":"CLOPIDOGREL","severity":"major","description":"Omeprazole inhibits | [] | [{"pmid":"16928254","title":"The Montreal definition and classification of gastroesophageal reflux d | K21.0 | "Affects approximately 18-28% of adults in North America; prevalence 10-20% in Western countries; on | ["digestive"] | Acid reflux | "Dr. Maura Callahan is an Irish-American board-certified gastroenterologist with 16 years of practic | "Denise Washington is a 54-year-old African-American woman who works as a school bus dispatcher. She | [{"role":"system","content":"You are Dr. Maura Callahan, a board-certified gastroenterologist in an | [{"mistake":"Labeling PPI failure without checking dose timing","explanation":"Omeprazole and esomep | [{"condition":"Stable angina or acute coronary syndrome","differentiating_factors":"Exertional chest | [{"disease":"Barrett's esophagus","relationship":"Intestinal metaplasia of the distal esophagus caus | "**Acid reflux (GERD, K21.0)** in a 54-year-old woman with obesity, rheumatoid arthritis on weekly m |
